A recent study suggests that individuals who stop using new weight-loss injections like Mounjaro or Wegovy can put back on lost weight much more quickly than those who halt traditional lifestyle plans.
Findings released in a prominent medical journal points out that while obese people frequently drop a large proportion of their body weight while using the jabs, the weight comes back at an estimated rate of nearly a kilo each month after stopping.
"People buying these drugs need to be informed of the potential of quick rebound weight gain when the treatment ends," cautioned expert Dr. Susan Jebb.
This pace of regain means a reversion to pre-treatment weight in about 18 months.
Weighing Treatments
The analysis, which examined dozens of studies involving thousands of patients, contrasted the results of these new drugs with other pills.
The team emphasize that people who shed pounds through diet and exercise typically see a slower creep back—perhaps 0.1 kg a month—post-intervention.
Explaining the Quick Regain
Experts propose the mode of action of the drugs accounts for the accelerated regain.
These medications imitate a body's own chemical called glucagon-like peptide-1, which controls appetite.
"Long-term administration of the hormone concentrations far above than normal might result in the system to produce less of its endogenous GLP-1, and may also lessen sensitivity to its actions," noted Dr. Adam Collins, a nutrition specialist.
"Withdrawal of this GLP-1 'fix' leads to appetite is no longer kept in check, making overeating a significant risk."
An Ongoing Issue?
The NHS recommend the jabs for people with weight-linked medical conditions, accompanied by recommended lifestyle changes.
Many experts say that, due to the significant potential of weight regain, the therapy might need to be long-term.
This perspective is reinforced by pharmaceutical companies, who state that the findings "highlight the long-term character of obesity," comparing it to managing conditions like diabetes.
User Experiences
Users who have stopped the jabs explain a powerful resurgence of hunger.
"It was like a trigger flipping and I was suddenly ravenous," said an individual.
This challenge is exacerbated if individuals have not developed sustainable lifestyle or habit modifications during treatment.
Widespread Adoption
Recent estimates indicate that a significant number of people in the UK have tried weight-loss jabs in the past year, with demand being substantial.
- Use is greater among women than men.
- The 40s and 50s age group shows the greatest level of interest.
- Many access the medications through private healthcare rather than public health services.
In conclusion, researchers stress that while these medications are effective tools for weight loss, they are not a magic cure and lasting health benefits likely depends on combined behavioural support.
